Bicarbonate dependence of ion current in damaged bone
نویسندگان
چکیده
منابع مشابه
Concentration dependence of bicarbonate-induced calcium current modulation.
High-voltage-activated calcium currents (HVA) of CA1 neurons are prominently attenuated following a switch from HEPES-buffered solution to one buffered with CO(2)/HCO(3)(-). In the present study we investigated whether bicarbonate ions or the dissolved CO(2) induce this alteration in current characteristic. The study was carried out on freshly isolated CA1 neurons using the whole cell patch-cla...
متن کاملCurrent state of bone scintigraphy protocols and practice in Japan
Objective(s): Nuclear medicine technologists in Japan often perform additional single-photon emission computed tomography (SPECT) with or without computed tomography (CT) after whole-body imaging for bone scintigraphy. In this study, we wanted to identify the bone scanning protocols used in Japan, together with the current clinical practices. Methods:...
متن کاملCurrent status of bicarbonate in CKD.
Metabolic acidosis was one of the earliest complications to be recognized and explained pathologically in patients with CKD. Despite the accumulated evidence of deleterious effects of acidosis, treatment of acidosis has been tested very little, especially with respect to standard clinical outcomes. On the basis of fundamental research and small alkali supplementation trials, correcting metaboli...
متن کاملLoad Dependence of Proximal Tubular Bicarbonate
Studies were undertaken in Munich-Wistar rats to determine whether maintenance of chronic metabolic alkalosis (CMA) is associated with an increase in proximal HCO3 reabsorption, or whether a reduction in glomerular filtration rate (GFR) is required to sustain the elevated plasma HCO3 concentration. Superficial single nephron glomerular filtration rate (SNGFR), and absolute proximal HCO3 (APRHCo...
متن کاملEnergy dependence of urinary bicarbonate secretion in turtle bladder.
Addition of HCO3- to the serosal side (S) of the isolated turtle bladder results in a HCO3- flow from S to the mucosal side (M) which markedly reduces the net rate of acid secretion. To characterize the driving forces for this downhill HCO3- flow, the effects of metabolic inhibitors and substrates were examined. In short-circuited bladders with the M pH lowered to the point of zero net H+ secr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Calcified Tissue International
سال: 1996
ISSN: 0171-967X,1432-0827
DOI: 10.1007/bf02509442